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Associate Professor Dr. Phakpum Panitchayupakaranan

Associate Professor Dr. Phakpum Panitchayupakaranan has given the research study on biological of spirulina as the following;


1. Placebo on immunization toward diseases
There has been report in discovery of Immulina which is one kind of cabohydrate in high molecula weight polysaccharide extracting from spirulina. According to the report, it is found that Immulina has the placebo on immunization in human body. It stimulates the monocytes and macrophages in human, which are the types of white blood cell. It is also found that Immulina has stronger placebo than the polysaccharide which now using for remedy the cancer with immunotherapy. In the present, around 100 to 1000 report that the test of spirulina as supplement in chicken, rat and cat food can increase immunity in all three kinds of animal. According to this report, it is found that spirulina help to increase the effectiveness of white blood cell of macrophages and NK-cell type. Moreover, it is reported that the extract from spirulina with hot water can increase immunity in human by increasing gamma-interferon and increase the effectiveness of white blood cell as well.

2. Antioxidant or radical scavenger
It is reported that C-Phycocyanin which extracted from Spirulina platensis has the antioxidant and radical scavenger both in the laboratory test in lab tube test and in animal test.

3. Anti-virus
It is reported that Spirulina platensis from water has anti-fission of Virus HIV-1 in white blood cell which feed in lab tube such as T-cell line and peripheral blood mononuclear cell. Besides it is also found that the extract from calcium spirulant is the strong substance use to prevent Herpes simplex virus type 1 and HIV-11. Therefore, Calcium Spirulant should be developed as antivirus for HIV. Besides it has the antivirus which can be the cause form many diseases such as common cold, measles, mumps and etc.

4. Anti hardening in blood
It is reported that calcium in spirulina has anti-hardening in blood properties. It helps to restrain ‘thrombin’ by stimulating the building of heparin cofactor II. So, Calcium in Spirulina can be the original medicine to develop any medicine that use to cure the disease of blood hardening.

5. Spirulina has the property of chemo- and radio-protective
There is a report that the chemical compound in polysaccharide group which extracting from Spirulina platensis has the capability to protect the danger causing from cyclophosphamide and gamma ray. It can be used to apply with other medicine in treating cancer. Moreover, the extract from C-Phycocyanin extracting from Spirulina platensis helps to decrease the toxic in liver causing from chemical satisfactorily.

6. Anti-spreading out of cancer cell
The laboratory test is reported that calcium spirulina have the capacity to restrain the spreading out of cancer cell type B16-BL6 melanoma in lung cell. It is also found that calcium spirulina have the ability to protect the attachmenet of cancer cell type B16-BL6 on basement membrane of lung cell as well.

7. Have the effect on working system of lipoprotein lipase and hepatic triglyceride lipase which have the important duty to digest fat.
This study test with guinea pig by feeding with high fructose at 68% to induce and causing of hyperlipidemia condition together with the use of different level of intensive spirulina extract which are 5%,10% and 15% for 4 weeks, then comparing with the guinea pigs which consuming only high fructose. According to this test, it is found that guinea pigs that consuming high fructose together with spirulina extract can increase the working system of lipoprotein lipase which resulting in the prevention for hyperlipidemia condition in diabetes patience.

8. Help to decrease Cholesterol level in blood
A research found that the rats which consume food containingg with 1% cholesterol and 16% spirulina can decrease the cholesterol and phospholipids in blood importantly. On the other hand, when comparing with another group of guinea pigs that consume the food contain only 1% cholesterol found that spirulina has given the effect to decrease the high cholesterol level in blood and atherosclerosis.

9. Anti-anaphylactic reaction
There are test that giving induce substance to the guinea pigs resulting in anaphylactic reaction by using with spirulina with different level of intense. It is found that spirulina effect on antibiosis of histamine (which has importantly result sudden anaphylactic reaction (allergic reaction) from mast cell. The result of this study point out that spirulina might have a substance which helps to prevent the dissolution of mast cell in guinea pigs.

10. Antiphlogistic
The research is reported that C-Phycocyanin extracting from spirulina have the capacity to specifically prevent cycloxygenase-2 (COX-2) resulting in antiphlogistic effect, consequencely with the previous research that C-Phycocyanin have the capacity to prevent the danger in liver and antiphlogistic in vertebrae.